One of Parrilla’s earliest on-camera jobs was an appearance in the Steven Spielberg movie of the week, Semper Fi (2001). Thereafter, she joined the cast as a regular on the hit comedy series Spin City.Parrilla has been a regular on many critically acclaimed shows such as Boomtown, where she played a young paramedic, for which she received an Imagen Award, 24, as a counter-terrorist agent, and Swingtown, as a sexually progressive woman in the 1970s, to name a few. She has also recurred on such memorable series as NYPD Blue, Six Feet Underand Lost.
Parrilla relished one of her most recent roles as Regina Mills/Evil Queen on the hit show Once Upon A Time. Working on the ABC series has garnered her some accolades including a NHMC Impact Award, an ALMA Award for Outstanding TV Actress, a Teen Choice Award for Choice TV Actress: Sci-Fi/Fantasy,as well as being voted by fans as TV Guide’s Best Villain.
Her most recent work is the David Ayer film The Tax Collector, starring alongside Shia LaBeouf, which should see a release later this year.